Ongoing and published protocols

Outcomes of patients undergoing aortic valvuloplasty in TAVI era: a multi center registry.

Introduction : Due to TAVI (Transcatheter aortic-valve implantation) patients with severe aortic stenosis and a large burden of both cardiac both non comorbidities are treated more invasively, with balloon aortic valvuloplasty (BAV) becoming more common, both as bridge to TAVI both as destination therapy.
Methods:All consecutive patients undergoing BAV in our center from 2005 to 2013 will be enrolled. All cause death at follow up will be the primary end point, while need for re-intervention, myocardial infarction, stroke the secondary ones along with BAV periprocedural complications adjudicated according to VARC (death, bleeding, vascular complications, acute kidney injury). Given an expected rated of death of 30% at one year (Saia et al, Eurointervenion 13) at least 200 patients are needed to accurately identify at least six clinical/interventional predictors of adverse events.
Involved Centers:
-PI: Division of Cardiology, Citta' Della Salute e Della Scienza, Turin, Italy (Dr Moretti)
- Division of Cardiology, San Giovanni Bosco, Italy (Dr Boccuzzi)
- Division of Cardiology, Maria Vittoria, Turin, Italy (Dr. Belli)
- Division of Cardiology, Siena, Italy (Dr. Petronio)
- Division of Cardiology, Milan, Italy (Dr. Presbitero)
- Division of Cardiology, Catania, Italy (Prof. Tamburino)
- Division of Cardiology, Siena, Italy (Dr. Palazzuoli)
- Division of Cardiology, Santander , Spain( Dr. De La Torre)
- Division of Cardiology, Nieuwegein, Holland (Dr. Ten Berg)
- Division of Cardiology, Brighton, UK (Dr. Hiddick Smith)
- Hospital de la Princesa, Madrid, Spain (Dr. J. Goicolea)
Principal investigator: Citta' della Salute e della Scienza, University of Turin, Italy
To join the protocol : drclamore [et]